Friday 27 March 2015

Why do people choose to proceed with PGD?

PGD (Pre-implantation Genetic Diagnosis) is a genetic test performed on human embryos prior to implantation into the woman’s uterus. IVF treatment first needs to be performed in order to enable PGD testing. With IVF treatment, embryos are created in a laboratory environment by the fertilization of a woman’s eggs with sperm. When the embryos reach 6-8 cell stage (usually 4-5 days after fertilization) a biopsy is taken from the embryo to perform a genetic test called PGD. PGD testing helps to determine if the embryo has any genetic anomalies. 

Humans have 23 pairs of chromosomes and in a typical PGD test, several pairs of these chromosomes most susceptible to genetic diseases are analyzed. There are many reasons why couples proceed with PGD.

In a typical PGD test the chromosomes, which are linked with Down syndrome and Trisomy are checked. The X, Y chromosomes, which determine the gender of the offspring is also checked for any genetic disease that may be passed on to a specific gender. This also enables the couple to know the gender and if desired to choose the gender of their offspring. This is commonly referred to as sex selection and is only allowed in a few countries like the USA, Cyprus and Thailand. In countries where sex selection is not allowed, the PGD testing is used to analyze gender related physical or mental anomalies. For example hemophiliac and Duchenne’s muscular dystrophy genetic disease is related with the X chromosome which only affects male embryos. 

To whom is PGD performed?

Couples wishing to become parents, but have genetic conditions in their families such as Tay-Sachs disease, cystic fibrosis, muscular dystrophy, sickle cell anemia or Huntington’s disease usually choose PGD to make sure their offspring will be free from these diseases.

In addition to couples with genetic disease in their family, PGD is also recommended for older woman looking to become pregnant as the rate of genetic anomalies increase with older age. Women suffering from a history of miscarriages are also advised to go through PGD to increase the likelihood of delivering a health baby. 

With today’s technology, virtually all chromosomes can be analyzed for genetic diseases. However, it is economically unfeasible to analyze each chromosome for every couple going through PGD testing. Therefore, in most cases, several pairs of chromosomes are analyzed that assesses the most common genetic disease. It is advisable to speak to your doctor if PGD is right for you and what type of PGD testing is recommended.

Take a look for further


  1. PGD involves extracting a cell from the IVF embryo and test it for some specific genetic condition or disorder like cystic fibrosis. Once it’s examined and identified to be safe, it’s transferred to the womb.

  2. PGD involves extracting a cell from the IVF embryo and test it for some specific genetic condition or disorder like cystic fibrosis. Once it’s examined and identified to be safe, it’s transferred to the womb.

  3. IVF Centre in India Click on the given source if you all want the best treatment of the fertility problem at reasonable price in India.

  4. Its quite different from other posts. Thanks for sharing.
    sexologist doctor in chennai

  5. I'm very sad Giuliana has to go through so much. I don't know why life is so much of a struggle to some of us.....sigh..... I hope and pray they will succeed and have a happy family one day.

    IVF Centre in Jalandhar | Low Cost IVF Treatment in Jalandhar

  6. In PGD, single cells from embryos are screened for any genetic disease and chromosome disorders. This test takes place during the IVF treatment and is done prior to embryo transfer. The objective of PGD is to identify abnormal embryos and discard them before they’re put in the womb.

  7. In my experience KIC is the best surrogacy clinic in hyderabad. They are providing a best treatment with well experienced doctors.

  8. Impressive work.IVF treatment performs various kind of testings.CM hospital is the best Fertility Centre in Chennai with individualized treatment and Gynecologist In Velachery will give you the best care, they are focused in your health and comfort.

  9. Your post is really good in explaining about the importance of PGD testing. Many couples didn't know about this test. It is important test to perform after the embryos transfer.

    IVF cost in hyderabad

  10. This is a very useful post, thank you! I agree that innovations are the most important thing for most businesses, because with today’s fast changing world we need to stay on top of the changes, if we want to survive.
    dystonia relief

  11. IVF is one such treatment in which if couples are unable to conceive naturally, egg and sperm are fertilised outside the body.Best IVF Centre in Delhi

    IVF Specialist in Delhi

    best IVF clinic in Delhi

  12. Are you looking for IVF treatment for pregnancy then SWCIC is the topmost fertility hospital in Hyderabad? We provide the best treatments IVF, IVM, IUI, ICSI, and laser hatching many more treatments. We offer advanced medical technologies and treatment styles for fertility and the success rate is very high. To book an appointment visit our website.

  13. Hey nice blog,Thanks for this helpful information come back again for more interesting information. Keep it up!
    Sperm Donation Cyprus

  14. Good Post and informative one. Thank you for sharing this good article.
    IVF Treatment In Greater Noida

  15. For many couples who are having problems conceiving, artificial insemination is the answer to becoming pregnant and having a child .thank you for your blog.
    Best fertility centre in Chennai
    Best ivf centre in Chennai
    Chennai fertility Center